Case 22: Guillain–Barré Syndrome with Early Functional Change
- Hill Yang

- Jan 18
- 2 min read
A male patient in his late 40s, with a background as a former athlete and physically demanding plumber, was referred following a confirmed diagnosis of Guillain–Barré syndrome (GBS). Prior to onset, he reported good general health and a high level of physical capacity.

The condition developed rapidly, with generalised weakness reported on the first day and progression to near-complete loss of voluntary movement within several days. At initial presentation, the patient was wheelchair-dependent, demonstrating profound muscle hypotonia, marked sensory impairment, and minimal voluntary control of all four limbs.
Medical history indicated a preceding viral illness and a delayed diagnostic process. Due to the risk profile associated with GBS, including potential respiratory involvement, the patient remained under continuous medical supervision during the early stages of recovery. Peripheral neuropathy was prominent, particularly affecting the lower limbs, with significant loss of muscle tone and postural control.
Intervention during this period focused on supporting neuromuscular engagement, postural loading tolerance, and functional movement tasks, delivered alongside ongoing medical and physiotherapy care. Following these sessions, gradual changes in lower-limb activation and postural stability were observed. On hospital reassessment the following day, the treating physiotherapy team determined that the patient could trial assisted ambulation using crutches.
At a subsequent session, clinical focus shifted toward gait consistency, balance strategies, and distal limb control within safe functional limits. By approximately day 38 post-onset, the patient presented using crutches and was able to ambulate short distances with reduced external support. Functional testing at that stage demonstrated improvements in balance, coordination, and voluntary muscle recruitment, particularly through the thighs.
Recovery trajectories in Guillain–Barré syndrome vary widely, often extending over many months or longer. In this case, the functional changes observed occurred earlier than typically anticipated, though ongoing recovery remained dependent on multiple factors. Continued medical oversight and interdisciplinary collaboration were recommended to support neurological recovery, monitor risk, and guide safe progression of daily activities.
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